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Exam 13: Host Defenses II: Specific Immunity and Immunization

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Question 1

Multiple Choice

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The molecular fragment on an antigen molecule that a lymphocyte recognizes and responds to is called a(n)

A) epitope.
B) hapten.
C) antigen binding site.
D) variable region.
E) None of the choices is correct.

F) A) and E)
G) B) and E)

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Question 2

True/False

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The hinge region of an antibody has a hypervariable amino acid region where the antigenic determinant fits.

A) True
B) False

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Question 3

Multiple Choice

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Antigens that elicit allergic reactions are called

Lymphocyte maturation involves

Small foreign molecules that are too small by themselves to elicit an immune response are termed

Which of the following is not a property of B cells?

The region of each antibody molecule where amino acid composition is highly varied from one clone of B lymphocytes to another is the

Which immunoglobulin class/es can fix complement?

What type of cells secrete antibodies?

Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. The Smith family has brought their 2-week-old son into your family practice office for his 2-week checkup. He is their first son, and they are very anxious. They have already expressed multiple concerns to you concerning sleep, feeding, and crying, but their concerns have been about things that are typical for a newborn. You try your best to calm their fears, and they are receptive for the most part. However, when it comes time to discuss vaccination with them, they refuse to vaccinate their son because they report they have heard vaccines can cause autism in children. -What kind of immunity will be conferred to the Smith's son through vaccination?

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is

Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Marie is a 57-year-old female who is on your general medical-surgical unit with a bladder infection. Two weeks ago, she was having slight burning upon urination. She self-treated with an increased intake of cranberry juice, but did not see any improvement. In fact, her symptoms got worse. Last week, she developed generalized abdominal pain and a mid-grade fever. She did not come into the hospital until the pain was unbearable and she had a fever of 104F. She was admitted to your unit and started on multiple IV antibiotics. The doctors say that she could be developing a kidney infection. -What is the proper order of steps for B-cell activation?

The secondary response to an antigen is faster and bigger than the primary response.

High titers of specific antibodies are components of

An example of artificial active immunity would be

One plasma cell will secrete antibodies of various classes but the antibodies will all have the same specificity.

Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. The Smith family has brought their 2-week-old son into your family practice office for his 2-week checkup. He is their first son, and they are very anxious. They have already expressed multiple concerns to you concerning sleep, feeding, and crying, but their concerns have been about things that are typical for a newborn. You try your best to calm their fears, and they are receptive for the most part. However, when it comes time to discuss vaccination with them, they refuse to vaccinate their son because they report they have heard vaccines can cause autism in children. -The morning after the Smith's son is vaccinated,Mrs.Smith calls you at the office to report that their son has now developed a low-grade fever.She is afraid that he is developing meningitis from one of the vaccines,because he is also fussy.What is a proper response?

The major histocompatability complex is

Antibodies directed to alloantigen from one organism often cross-react with an alloantigen from another organism.

Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Joseph is a 6-year-old male presenting to your pediatric office with chickenpox. He has had his infection for about 1 week, and his mom is concerned about Joseph’s 8-year-old sister, Judith, because she had a long, painful infection of chickenpox 2 years before. Of note, Joseph was not vaccinated against chickenpox when he was younger, because his mom did not think it was that serious of a virus, and she wanted to spare him the extra injection. -Which form of immunity is Joseph developing by having this infection?