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A collection of genes or operons controlled by a common regulatory protein is called a(n) ___________ .

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When a repressor binds to the operator site on the DNA it normally


A) inhibits the initiation of transcription.
B) reduces the rate of transcription.
C) terminates transcription that has already been initiated.
D) has no effect on transcription.

E) All of the above
F) B) and C)

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The


A) one
B) two
C) three
D) four
E) coli lac operon has ________ operator sequences.

F) D) and E)
G) C) and D)

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So-called two-component regulatory systems


A) include a sensor kinase and a response regulator.
B) play a key role in regulating sporulation in Bacillus.
C) play a key role in regulating the OmpF and OmpC porin proteins in
D) all of the choices
E) coli.

F) B) and E)
G) D) and E)

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D

Which of the following is not a regulatory mechanism used to control the tryptophan operon in Escherichia coli?


A) repression
B) catabolite repression
C) attenuation
D) all of the choices

E) A) and C)
F) A) and D)

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The sensor kinase for the OmpF: OmpC two-component regulatory system is


A) the OmpK protein.
B) the EnvZ protein.
C) the MicF RNA.
D) none of the choices.

E) A) and D)
F) B) and C)

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B

The standard or housekeeping sigma factor used most often by


A) 70
B) 32
C) S
D) E
E) coli RNA polymerase under normal growth conditions is called sigma ___.

F) B) and D)
G) A) and B)

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Cell-to-cell communication by quorum sensing has been shown to be important in the regulation of genes needed for


A) virulence.
B) biofilm production.
C) plasmid transfer.
D) all of the choices.

E) None of the above
F) All of the above

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The binding of arabinose to the AraC protein allows it to form a loop in the DNA upstream of the ara operon promoter.

A) True
B) False

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False

____________ is used to measure the amount of a chemoattractant encountered over time.

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Most


A) CAP
B) MicF
C) Hfq
D) none of the choices
E) coli antisense RNAs work with a protein called ______ to regulate their target mRNAs.

F) A) and D)
G) A) and E)

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During sporulation in Bacillus subtilis, the response regulator that positively controls many genes needed for sporulation and negatively controls genes not needed during sporulation is


A) SpoOB
B) SpoOA
C) SpoOF
D) SpoOC

E) None of the above
F) C) and D)

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During the early stages of sporulation in Bacillus subtilis, ________ is active in the forespore and ________ is active in the mother cell.


A) σ\sigma E; σ\sigma F
B) σ\sigma K; σ\sigma F
C) σ\sigma F; σ\sigma K
D) σ\sigma F; σ\sigma E

E) B) and C)
F) A) and D)

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Bacteria, Archaea, and Eukarya differ in both their genome structure as well as in the steps required to complete gene expression.

A) True
B) False

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Riboswitches that can block the initiation of translation because of a conformational change that occurs in the leader sequence of an mRNA when the appropriate regulatory effector binds the mRNA achieve that blockage of translation initiation by the occlusion of


A) the promoter
B) the attenuator
C) the Shine-Delgarno sequence
D) the AUG start codon

E) None of the above
F) A) and D)

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When bound to the DNA, the repressor protein usually prevents attachment of the RNA polymerase to the __________.


A) operon
B) operator
C) promoter
D) regulator

E) A) and C)
F) A) and B)

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Posttranslational regulation occurs after a protein has been synthesized, and can occur by


A) allosteric control
B) feedback inhibition
C) covalent modification
D) allosteric control and covalent modification are both means of regulation after translation is complete

E) A) and B)
F) A) and C)

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Regulation of gene expression serves to do all of the following except


A) conserve energy and raw materials
B) maintain balance between the amounts of various cell proteins
C) adjust the activity of existing proteins in the cell
D) adapt to long-term environmental change

E) All of the above
F) B) and C)

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Two-component signal transduction systems are found in the Bacteria, but not in Archaea.

A) True
B) False

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The site on the DNA to which a repressor protein binds is the __________.


A) operon
B) operator
C) promoter
D) regulator

E) None of the above
F) All of the above

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